The InvFEST database is temporarily out of service
The InvFEST Database website is temporarily unavailable due to the recently discovered PHP vulnerability. We are working on an improved version of the database with updated information and new functionalities, but it will take some time.
We apologize for any inconvenience and please contact us if you need any information on human inversions or are interested in contributing to the new database.
About the project
InvFEST aims to become a reference site to share information and collaborate towards the complete characterization of human polymorphic inversions. It is a data-warehouse implementation that integrates several data of interest related to inversions with an online analytical processing engine (OLAP) to gather information and compute a report of each inversion.
The InvFEST database stores and merges inversion predictions from healthy individuals into a non-redundant dataset by overlapping the position of the breakpoints of each prediction and taking into account the resolution of each study. Most predictions come from mapping information of paired-end sequences (PEM) obtained by different studies of the literature, which in some cases have been reanalyzed by GRIAL, a program specifically designed to detect inversions from PEM data. Moreover, it stores information of validations and genotyping assays, frequency in different populations, association with genes and segmental duplications, and the evolutionary history of the inversions.
The database will keep on updating information by incorporating new predictions, validations, genotyping data, and any other information, either extracted from peer reviewed research studies or generated in our lab. We always welcome your suggestions and comments.
